Disease encyclopedia/Mental health
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    Mental healthMental health conditionICD-10 F31

    Bipolar disorder

    Also called: Manic depression

    A lifelong condition with episodes of depression and episodes of mania or hypomania — abnormally elevated mood, energy and activity.

    Condition-specific references are below. Individual claims and this page have not been clinically reviewed. Read about this content.

    Affected: Brain

    Causes

    • Strong genetic component with environmental triggers

    Risk factors

    • Family history
    • Stress
    • Sleep disruption
    • Substance use
    • Antidepressants alone can trigger mania

    Symptoms

    • Mania: little need for sleep, racing thoughts, grandiosity, risky behaviour, rapid speech
    • Depressive episodes
    • Psychotic symptoms in severe episodes

    Diagnosis — tests and examinations

    • Psychiatric assessment and history from family
    • Mood charting

    Treatment

    Medicines and medical treatment

    • Mood stabilisers: lithium (most effective for prevention), valproate (avoided in pregnancy), lamotrigine
    • Antipsychotics (quetiapine, olanzapine, aripiprazole)

    Self-care, home remedies and lifestyle

    • Regular sleep and routines
    • Psychoeducation and relapse plans
    • Avoid alcohol and drugs
    • Psychological therapy

    Possible complications

    • Suicide
    • Relationship, financial and occupational harm

    Prevention

    • Early recognition of warning signs prevents relapse

    Outlook

    Most people live full lives with long-term treatment.

    When to see a doctor

    Seek urgent help for thoughts of suicide or severe mania.

    Sources and further reading

    These sources cover this condition. They have not been checked against every statement on this page.

    • Bipolar Disorder — MedlinePlus (U.S. National Library of Medicine)

    Related conditions

    DepressionAnxiety disordersSchizophreniaPost-traumatic stress disorderAttention deficit hyperactivity disorderAutism spectrum disorder

    Educational overview, not medical advice. Treatment varies by person and location. Consult a qualified health professional for diagnosis or care. Read our content and model notes and privacy information.

    Affected: Brain

    See it in 3-D

    Left cerebral hemisphere

    Anatomy

    • Left cerebral hemisphere

    On this page

    • Causes
    • Risk factors
    • Symptoms
    • Diagnosis — tests and examinations
    • Treatment
    • Complications
    • Prevention
    • Outlook
    • When to see a doctor
    • Sources